Investigation of Benegut® on Immediate GI Discomfort Relief Caused by Acute Overfeeding in Healthy Subjects

Inclusion Criteria: * Healthy volunteers without clinical diagnosed diseases with relevant effect on the gastrointestinal system or on visceral motility. * Age ≥ 25 and ≤ 70 years * BMI: 19-30 kg/m2 * Overall GI discomfort after high caloric meal of at least 5 on the VAS scale * Male or female * Written consent to participate in the study * Subject is able and willing to follow the study protocol procedures * If applicable, stable intake of chronic medication of at least 3 months Exclusion Criteria: Criteria for inclusion: * Healthy volunteers without clinical diagnosed diseases with relevant effect on the gastrointestinal system or on visceral motility. * Age ≥ 25 and ≤ 70 years * BMI: 19-30 kg/m2 * Overall GI discomfort after high caloric meal of at least 5 on the VAS scale * Male or female * Written consent to participate in the study * Subject is able and willing to follow the study protocol procedures * If applicable, stable intake of chronic medication of at least 3 months Criteria for exclusion: * Relevant history, presence of any medical disorder (e.g. cancer, severe liver disease, severe renal disease, severe cardiovascular disease) * Subject under prescription for medication for digestive symptoms such as anti-spasmodic, laxatives and anti-diarrheic drugs or use of PPI (proton pump inhibitors) or other digestive auxiliaries potentially interfering with this study at screening * Intake of antibiotics in the last 4 weeks * Women suffering from distinct PMS sympt…