UnknownNot Applicable

Renal Perfusion Assessment in the Endovascular Treatment of Renal Artery Stenosis

China30 participantsStarted 2020-11-04

Plain-language summary

The clinical benefits of endovascular treatment in renal artery stenosis remain controversial. This study uses arterial spin labelling MRI and flat-panel detector parenchymal blood volume imaging to observe the change in renal perfusion after endovascular treatment in renal artery stenosis.

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients who provided informed consent * patients who were diagnosed with RAS by CTA, MRA, or Doppler ultrasonography * patients who were aged 18 years or older * patients whose intervened renal arteries were not completely occluded (confirmed by DSA) * the stenosis percentage exceeding 70% * patients who had uncontrolled blood pressure or impaired renal function * paitents whose affected kidney did not have total loss of function Exclusion Criteria: * were pregnant * had a history of renal transplantation or renal artery bypass surgery * were allergic to iodine contrast medium * had other contraindications of endovascular treatment * contraindications of MRI examinations * had technical failure in the endovascular treatment.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Perfusion of the target kidney assessed by Arterial Spin Labelling MRI

Timeframe: Changes from baseline renal perfusion at 2 months

Perfusion of the target kidney assessed by Flat-panel Detector Parenchymal Blood Volume Imaging

Timeframe: Changes from baseline renal perfusion immediately after endovascular intervention

Trial details

NCT IDNCT05603221

SponsorPeking Union Medical College Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-06-30

Contact for this trial

Bao Liu

010-69152592 liubao72@aliyun.com

View on ClinicalTrials.gov More Renal Artery Stenosis trials