CompletedNot Applicable

Repetitive Transcranial Magnetic Stimulation in Hemiplegic Shoulder Pain

Turkey (Türkiye)18 participantsStarted 2022-10-01

Plain-language summary

Shoulder pain after stroke is one of the most common complications of stroke. Underlying mechanisms of shoulder pain after stroke still completely is not clarified. Central sensitization and neuropathic pain mechanisms are thought to play a role in the etiology of pain. Research on repetitive transcranial magnetic stimulation therapy in the treatment of pain in which somatosensory sensitization mechanisms play a role is increasing day by day. There are studies showing that application of high-frequency rTMS to the primary motor cortex provides effective pain relieving in most of painful conditions. However, data in the literature regarding the application of high-frequency rTMS in shoulder pain after stroke are very limited. There is only one clinical study related to this. More studies are needed in this area.In our study, it was aimed to examine the effects of this treatment protocol applied on the effects of pain on daily activities, upper extremity disability, anxiety, depression, range of motion and neurophysiological parameters.

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Being between the ages of 18-70 * Presence of ischemic or hemorrhagic stroke confirmed by MRI * Having a stroke for the first time * Presence of stroke in the subacute or chronic period * Presence of subacute or chronic shoulder pain starting after stroke and Numeric Rating Scale \>4 * If the patient is receiving analgesic treatment, the pain persists despite at least one week of analgesic treatment. * Patients who agreed to participate by signing the informed permission form. Exclusion Criteria: * Presence of history of surgical intervention on the shoulder joint * Presence of history of peri/intraarticular injection into the shoulder joint * Rotator cuff injury or tendonitis, frozen shoulder, etc. that they had diagnosed/treated before stroke * Presence of full-thickness rotator cuff tear visualized by US * Presence of \>3 spasticity in the upper extremity defined according to the Modified Ashworth Scale * Presence of severe cognitive impairment * Presence of aphasia * History of malignancy or systemic rheumatic disease * Alcohol or drug addiction * History of psychiatric illness such as major depression/personality disorders * History of epilepsy or taking medication due to epilepsy * Diagnosed with dementia * Pregnancy and breastfeeding * Having received TMS treatment before * Having a clinical condition (metallic implant, cardiac pace, head trauma, cranial operation history…) that would be a contraindication for TMS

What they're measuring

Change from baseline in the Numeric Rating Scale

Timeframe: (1) at the beginning of the treatment, (2) at the 1st week, (3) at the 2nd week, (4) at the end of the treatment (3rd week), (5)one month after the end of the treatment

Trial details

NCT IDNCT05601921

SponsorIzmir Katip Celebi University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-07-14