Angled-tip vs. Straight-tip Guidewire in Biliary Cannulation (NCT05600270) | Clinical Trial Compass
CompletedNot Applicable
Angled-tip vs. Straight-tip Guidewire in Biliary Cannulation
United States70 participantsStarted 2022-10-22
Plain-language summary
The investigators aim is to compare outcomes between an angled-tip guidewire and a straight-tip guidewire in cannulation of the common bile duct during ERCP. This is a randomized, controlled, single-blinded study. The primary outcome is success of cannulation and secondary outcomes are incidence of post-ERCP pancreatitis, procedure duration, and rate of complication between the angled wire and straight wire.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* patients undergoing ERCP for cholangiography, bile or tissue sampling from the gallbladder or bile duct
* patients undergoing ERCP for treatment of biliary diseases (removal of common bile duct stones, biliary stent placement)
Exclusion Criteria:
* Patients who are less than 18 years old
* Pregnant patients
* Patients who have undergone previous bile duct cannulation or sphincterotomy
* Patients who have undergone prior endoscopic balloon dilation or needle-knife fistulotomy
* Patients who have undergone gastric surgery (Billroth gastrectomy II, Roux-en-Y gastric bypass)
* Patients with acute pancreatitis
* Patients who refuse endoscopic intervention
* Patients with ampullary tumor, duodenal stenosis, or pre-operatively proven pancreaticobiliary malunion
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.