RecruitingNot Applicable

Iodine Uptake After a Low Iodine Diet

Netherlands25 participantsStarted 2023-02-22

Plain-language summary

The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days. The main question it aims to answer is: • What is the difference in iodine uptake before and after a LID of 7 days? Uptake of a low dose of 123-iodine will be measured in participants before and after a low iodine diet of 7 days. Researchers will compare the uptake (%) before and after the LID.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients, men and women above the age of 18 years, have to be diagnosed with DTC and have to follow a LID prior to the 131I ablation therapy according to the Dutch DTC guideline * Patients have to be fit to adhere to the study protocol * Patients have to be able to read and understand the Dutch language Exclusion Criteria: * Age \< 18 years * Patients using amiodarone * Patients receiving iodinated contrast \< 3 months before the LID * Pregnancy * Patients prepared for ablation therapy with rhTSH * Renal impairment, EGFR \<30ml/min/1,73m2

What they're measuring

Iodine uptake

Timeframe: 7 days

Trial details

NCT IDNCT05599139

SponsorUniversity Medical Center Groningen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-30

Contact for this trial

Wouter Zandee, Dr.

+31503613731 w.t.zandee@umcg.nl

View on ClinicalTrials.gov More Differentiated Thyroid Cancer trials