Assessment of Autologous Blood Marker Localization in Laparoscopic Colorectal Cancer Surgery (NCT05597384) | Clinical Trial Compass
UnknownNot Applicable
Assessment of Autologous Blood Marker Localization in Laparoscopic Colorectal Cancer Surgery
China220 participantsStarted 2022-11-01
Plain-language summary
Laparoscopic colorectal surgery has been proved to have similar oncological outcomes with open surgery. Due to the lack of tactile perception, surgeons may have misjudgments in laparoscopic colorectal surgery. Therefore, the accurate localization of a tumor before surgery is important, especially in the early stages of cancer. Recently, some retrospective studies reported the use of patients' autologous blood for preoperative colonic localization in colorectal cancer with successful detection by laparoscopy, but its benefits remain controversial. This study aimed to assess the accuracy and safety of autogenous blood marker localization in laparoscopic radical resection for colorectal cancer.
Who can participate
Age range18 Years – 80 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Age from 18 to 80 years
✓. Large lateral spreading tumors that could not be treated endoscopically, serosa-negative malignant colorectal tumors (≤ cT3), and malignant polyps treated endoscopically that required additional colorectal resection.
✓. The tumor is located in the colon, middle and high rectum (the lower margin of the tumor does not exceed peritoneal reflexes)
✓. No distant metastasis.
✓. American Society of Anesthesiology score (ASA) class I-III
✓. Performance status of 0 or 1 on Eastern Cooperative Oncology Group scale (ECOG)
✓. Written informed consent
Exclusion criteria
✕. BMI \> 35kg/m2
✕. Previous history of gastrointestinal surgery that altered the gastrointestinal anatomy.
✕. Pregnant or lactating women
What they're measuring
1
Autogenous blood marker localization was not inferior to intraoperative colonoscopy localization
Timeframe: From the beginning of endoscopic tattooing to the end of the surgery.