CompletedNot Applicable

Evaluation of the Effectiveness of an Amnion-chorion Membrane for Alveolar Ridge Preservation

United States30 participantsStarted 2022-11-16

Plain-language summary

This study will examine whether adding an amnion-chorion membrane on top of the traditionally used collagen plug will lead to more bone formation compared to the collagen plug only.

Who can participate

Age range20 Years – 80 Years

SexALL

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Inclusion criteria

✓. Age range: 20 to 80 years.
✓. Patients must require tooth extraction (for incisors, canines and premolars) as a result of caries, periodontal disease, tooth fracture or deemed unrestorable.
✓. Socket should be free of infection, less than 5mm of dehiscence
✓. Patients interested in implant placement following tooth extraction.

Exclusion criteria

✕. Allergies or hypersensitivities to study related medications such as chlorhexidine.
✕. Hematologic disorders/blood dyscrasias.
✕. Active infectious diseases of any kind.
✕. Liver or kidney dysfunction/failure.
✕. Uncontrolled diabetes (HbA1c \> 8).
✕. Active cancer treatment - such as active chemotherapy or radiation therapy.
✕. Taking medications that will affect their bone healing (for example, bisphosphonates).
✕. Metabolic bone diseases that affect bone healing such as osteoporosis.

What they're measuring

Clinical alveolar ridge dimension changes

Timeframe: 4 months

Digital alveolar ridge dimension changes

Timeframe: 4 months

Trial details

NCT IDNCT05592158

SponsorUniversity of Michigan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-14

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