People lose collagen all over the body, not just in the face; skin roughness and laxity of the dorsum of the hands can result from chrono and photo-aging. This skin roughness and laxity can range from very mild to severe; injection procedures can provide new tone and firmness to the skin of the hand dorsum. Dermal fillers are the most used non-permanent injectable materials available today to correct skin flaccidity and roughness on the dorsum of the hands. They give immediate aesthetic effect due to elastic gel matrix injected and impart longer term effects due to bio stimulation, promoting new collagen formation. The objective of this study is to investigate the aesthetic performance of the Hyaluronic acid (HA)- based dermal filler Profhilo® Body injected by a blunt tip microcannula (25G or 22G, preferably 22G), with fanning technique through a single entry point performing 5 passages and injecting 0,3 ml per passage, 1,5 ml for each hand. Volunteers of both sexes, aged 18-65 years with mild-moderate skin roughness and laxity at the level of hand dorsum are to be treated.
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Change from Baseline of Skin Roughness and flaccidity at 30 days and at 120 days post-injection
Timeframe: Day 0, Day 30, Day 120
Change from Baseline of Skin density (profilometry) at 30 days and at 120 days post-injection
Timeframe: Day 0, Day 30, Day 120
Change from Baseline of Superficial and deep skin plastoelasticity at 30 days and at 120 days post-injection
Timeframe: Day 0, Day 30, Day 120
Change from Baseline of Tissue dielectric constant value of superficial and deep skin layers at 30 days and at 120 days post-injection
Timeframe: Day 0, Day 30, Day 120
Change from Baseline of Photographic evaluation at 30 days and at 120 days post-injection
Timeframe: Day 0, Day 30, Day 120