Active — Not RecruitingPhase 4

Statins in Reducing Events in the Elderly Mind (STAREE-Mind) Imaging Substudy

Australia341 participantsStarted 2019-09-19

Plain-language summary

The STAREE-Mind imaging sub-study will examine the effect of statin treatment over a 4-year period, compared with placebo, on markers of brain health.

Who can participate

Age range70 Years

SexALL

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Inclusion Criteria: * Participants in the STAREE RCT and eligible for randomisation to study medication. * Men and women * Aged ≥70 years * Living independently in the community * Willing and able to provide informed consent and agree to participate in brain neuroimaging. * Able to attend one of the 2 sites (in Melbourne and Brisbane) where the imaging will take place. Exclusion Criteria: * Contraindications to have magnetic resonance neuroimaging performed. * History of invasive brain surgery or known structural bran abnormalities.

What they're measuring

Free water

Timeframe: Change from baseline to four years

White matter hyperintensity volume

Timeframe: Change from baseline to four years

Trial details

NCT IDNCT05586750

SponsorMonash University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09

View on ClinicalTrials.gov More Dementia, Mixed trials