To determine whether a short course of oral flucloxacillin (5 days) is non-inferior to a standard course (7 days) in terms of pain over days 6-14 (indicative of persistence or recurrence associated with the symptoms of most importance to patients) in adults with cellulitis of the leg presenting in primary care.
Who can participate
Age range18 Years
SexALL
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Inclusion Criteria:
* Must be aged 18 years or older
* Currently showing symptoms of cellulitis (such as pain, tenderness, redness, other change in skin color, warmth to touch) in one leg for 10 days or less
* Pain rated as 3/10 or higher on a numerical rating scale (0-10) at baseline assessment
* Be willing to be randomized to either trial arm (5-day or 7-day treatment)
* Able to complete trial procedures in the English language.
Exclusion Criteria:
* Have penicillin allergy
* Have bilateral cellulitis
* Have had antibiotics for cellulitis within the past month
* Have post-operative cellulitis (within 30 days of operative procedures on the same leg)
* Have cellulitis resulting from human/animal bite injury
* Have Cellulitis associated with chronic (\>6 weeks) leg ulceration
* Require immediate hospital admission or out-patient intravenous antibiotic therapy