Intracoronary ECG ST-segment Shift Remission Time During Reactive Coronary Hyperemia (NCT05583786) | Clinical Trial Compass
UnknownNot Applicable
Intracoronary ECG ST-segment Shift Remission Time During Reactive Coronary Hyperemia
Switzerland120 participantsStarted 2022-06-01
Plain-language summary
This study evaluates a new diagnostic approach based on intracoronary electrocardiogram (icECG) ST-segment shift remission time, denoted as τ-icECG (τ=tau, i.e., the remission half-time fitted by an exponential function to the disappearing ST-segment shift), to be used for PCI guidance.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Chronic coronary syndrome
* Chronic stable 1-3 vessel coronary artery disease
* Coronary stenotic lesion of any diameter narrowing
* Age \> 18 years
* Referred for elective coronary angiography to the investigators institution
* Written informed consent to participate in the study
Exclusion Criteria:
* Acute coronary syndrome
* Unstable cardiopulmonary condition
* Severe aortic valve stenosis
* Acute congestive heart failure NYHA (New York Heart Association) III-IV
* ECG bundle branch blocks, non-sinus rhythm or paced rhythm
* Coronary anatomy unsuitable for coronary measurements
* Severe pulmonary, renal or hepatic disease
* Women of childbearing age (≤50years and ≤12months after the last menstruation)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
icECG ST-segment shift remission time (τ-icECG)
Timeframe: once after a 1-minute coronary ballon occlusion