As concerns regarding the effects of agriculture on human and environmental health mount, a growing number of farmers are seeking ways to improve health from the ground up. A promising way by which a growing number of farmers are seeking to improve environmental health is by using agro-ecological practices (i.e., farming more closely in harmony with natural systems), which include practices such as multi-cropping, ley rotations, and/or integrated crop-livestock systems. Despite potential ecological benefits, there is a lack of critical knowledge if consuming foods from agro-ecological systems impacts biomarkers of human health, including inflammatory and metabolomics profiles. The purpose of this project is to test the hypothesis that consuming foods produced using agro-ecological practices improves biomarkers of consumer health compared to consuming similar foods from conventional (monoculture) agriculture. All diets will be matched one-to-one in terms of macronutrients and food sources.
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Inflammatory cytokine biomarker (IL-6 and TNF-alpha) concentrations in plasma samples
Timeframe: Day 44 (post)
Inflammatory cytokine biomarker (C-reactive protein) concentrations in plasma samples
Timeframe: Day 44 (post)
Relative abundance of metabolites in plasma samples using triple quad LC/MS-MS
Timeframe: Day 44 (post)
Composition of gut microbiota bacteria using 16s rRNA sequencing
Timeframe: Day 44 (post)