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The Comparison of Thick Split-thickness Skin Graft Versus Thin Split-thickness Skin Graft

China40 participantsStarted 2022-05-01

Plain-language summary

In clinical settings, split-thickness skin graft (STSG) remain the gold standard for covering large skin defects. However, STSGs usually bring complications to the donor sites. The study objective was to compare the efficacy of thick split-thickness skin graft versus thin split-thickness skin graft in the reconstruction of the donor site.

Who can participate

Age range20 Years – 80 Years

SexALL

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Inclusion criteria

✓. Patients had skin defects at functional sites or joint sites.
✓. Patients aged 20-80 years.
✓. The lateral thighs were chosen as the donor sites.

Exclusion criteria

✕. Patients who were unable to complete the follow-up.
✕. Pregnant or nursing mothers were not included.
✕. Patients had an alternative source of pain other than surgical sites.
✕. Patients with organ dysfunctions (heart failure, respiratory failure, liver dysfunction, renal impairment or intestinal failure), or cancers.
✕. Patients with autoimmune diseases (rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, Sjogren's syndrome, connective tissues disease or systemic vasculitis) were not included.
✕. Patients who had medications (such as corticosteroids, immunosuppressive agents or chemotherapy) within six months were not included.
✕. Other reasons.

What they're measuring

healing time of the donor sites

Timeframe: 2 months post surgery

Trial details

NCT IDNCT05571904

SponsorNanjing First Hospital, Nanjing Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12-01

Contact for this trial

Yin Wu, phD

18305155832 medwuyin@163.com

View on ClinicalTrials.gov More Reconstruction trials