Balloon + Oxytocin Versus Oral Misoprostol to Induce Labor in Case of PROM (RUBAPRO2)

Inclusion Criteria: * Age \> 18 years old, * Pregnant, Gestational age ≥ 37 weeks * Singleton pregnancy with cephalic presentation * Nulliparous * PROM without labour beyond 12 hours * Unfavourable cervix (Bischop score \< 6) * Able to give her informed consent * Ability to comply with the requirement of the study * Covered by the French Social Security welfare system Exclusion Criteria: * Unable to understand French language * Contraindication for vaginal delivery * Loss of meconium amniotic fluid (LA) * Temperature \> 38.2°C * Intrauterine infection * IUGR with Doppler anomaly * Fetus with expected polymalformative syndrome * Scarred womb * Suspicion of genital herpes * Known HIV seropositivity * Placenta praevia * Fetal death * Abnormal FHR (Fetal Heart Rate) * Contraindication to misoprostol: * Allergy or hypersensibility * Suspicion or confirmation of a scarred uterus following past surgical intervention * Renal insufficiency * Malformation of the uterus * Contraindication to balloon: * Vasa praevia, placenta praevia * Invasive cervical cancer * Contraindication to oxytocin * Allergy or hypersensibility * Dystocia * Fragility or excessive distension of the uterus * Uterine hypertonia or fetal distress when delivery is not imminent * Cardiovascular disorders and severe preeclampsia * Predisposition to amniotic embolism (in utero fetal demise, abruption). * Patient subject to a legal protection order (curatorship or tutorship) * Refusal to par…