CompletedNot Applicable

A Real-world Comparison of FNB and FNA in IHC-required Lesions.

China439 participantsStarted 2014-12-01

Plain-language summary

Endoscopic ultrasound (EUS)-guided fine needles with side fenestrations are used to collect aspirates for cytology analysis and biopsy samples for histologic analysis. The investigators conducted a large, multicenter study to compare the accuracy of diagnosis via specimens collected with fine-needle biopsy (FNB) versus fine-needle aspiration (FNA) for patients with lesions requiring immunohistochemistry (IHC) pathological diagnosis.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age \>18 years; * presence of a solid mass lesion was confirmed by at least 1 imaging modality and it was located within pancreas, abdomen, mediastinum, or pelvic cavity; * mass size \>1 cm; * final diagnoses were obtained after surgery, imaging analysis, or resolution of the lesion, including AIP, NET, mesenchymal tumors, and lymphoma. Exclusion Criteria: * coagulopathy (international normalized ratio, 1.5); * thrombocytopenia (platelet count \<50,000/mm3); * acute pancreatitis within the previous 2 weeks; * inability to safely perform EUS-TA (eg, cardiorespiratory dysfunction, mental diseases, or drug addiction); * refusal or inability to provide an informed consent.

What they're measuring

Diagnostic yields of EUS-FNA with EUS-FNB for solid masses

Timeframe: From admission until the date of pathological diagnosis obtained or follow-up up to 24 months

Diagnostic yields of EUS-FNA with EUS-FNB for solid masses

Timeframe: From admission until the date of pathological diagnosis obtained or follow-up up to 24 months

Diagnostic yields of EUS-FNA with EUS-FNB for solid masses

Timeframe: From admission until the date of pathological diagnosis obtained or follow-up up to 24 months

Diagnostic yields of EUS-FNA with EUS-FNB for solid masses

Timeframe: From admission until the date of pathological diagnosis obtained or follow-up up to 24 months

Trial details

NCT IDNCT05565066

SponsorHuazhong University of Science and Technology

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-09-30

View on ClinicalTrials.gov More Neuroendocrine Tumors trials

Plain-language summary

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Diagnostic yields of EUS-FNA with EUS-FNB for solid masses

Timeframe: From admission until the date of pathological diagnosis obtained or follow-up up to 24 months

Diagnostic yields of EUS-FNA with EUS-FNB for solid masses

Timeframe: From admission until the date of pathological diagnosis obtained or follow-up up to 24 months

Diagnostic yields of EUS-FNA with EUS-FNB for solid masses

Timeframe: From admission until the date of pathological diagnosis obtained or follow-up up to 24 months

Diagnostic yields of EUS-FNA with EUS-FNB for solid masses

Timeframe: From admission until the date of pathological diagnosis obtained or follow-up up to 24 months