CompletedNot Applicable

Efficacy of Phonophoresis With Topical Glyceryl Trinitrate in Treatment of Achilles Tendinopathy

Egypt64 participantsStarted 2022-11-01

Plain-language summary

The aim of study is to investigate the effect of Phonophoresis with topical glyceryl trinitrate versus traditional treatment in in patients with non-insertional Achilles tendinopathy.

Who can participate

Age range20 Years – 50 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Age between 20-50 years old
✓. The diagnosis was based on pain located in the Achilles tendon for at least 3 months.
✓. Pain in the Achilles tendon area with distinct tenderness of the tendon 2 to 6 cm above the Achilles tendon insertion on the calcaneus
✓. Ultrasonographic changes defined as local thickening of the symptomatic tendon, irregular tendon structure and fiber orientation, and separated tendon fibers or a globally more than 2 mm thicker tendon on the sick side
✓. Diffuse pain in the posterior region of the ankle with local tenderness of the Achilles tendon and ultrasonographic changes.

Exclusion criteria

✕. Symptoms of \<3 months, previous surgery, previous ankle dislocation, distal neurology, steroid injections in last 3 month, pregnancy, and contraindication to GTN
✕. Treatment of achillodynia with stretching or eccentric training for more than 2 weeks within the last 2 years
✕. Other injuries in the lower extremity or the knee, which by the examining doctor was evaluated to influence the evaluation of symptoms or the ability to perform the training program
✕. Acute symptoms with ultrasonographic changes consistent with a partial rupture of the tendon

What they're measuring

the change in thickness of Achilles tendon

Timeframe: at first week and after 12 week of treatment

the change in Pain in patients with non-insertional Achilles tendinopathy.

Timeframe: at first week and after 12 week of treatment

the change in Functional performance

Timeframe: at first week and after 12 week of treatment

Trial details

NCT IDNCT05561959

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-02-01

View on ClinicalTrials.gov More Non Insertional Achilles Tendinopathy trials

Who can participate

Age range20 Years – 50 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Age between 20-50 years old
✓. The diagnosis was based on pain located in the Achilles tendon for at least 3 months.
✓. Pain in the Achilles tendon area with distinct tenderness of the tendon 2 to 6 cm above the Achilles tendon insertion on the calcaneus
✓. Ultrasonographic changes defined as local thickening of the symptomatic tendon, irregular tendon structure and fiber orientation, and separated tendon fibers or a globally more than 2 mm thicker tendon on the sick side
✓. Diffuse pain in the posterior region of the ankle with local tenderness of the Achilles tendon and ultrasonographic changes.

Exclusion criteria

✕. Symptoms of \<3 months, previous surgery, previous ankle dislocation, distal neurology, steroid injections in last 3 month, pregnancy, and contraindication to GTN
✕. Treatment of achillodynia with stretching or eccentric training for more than 2 weeks within the last 2 years
✕. Other injuries in the lower extremity or the knee, which by the examining doctor was evaluated to influence the evaluation of symptoms or the ability to perform the training program
✕. Acute symptoms with ultrasonographic changes consistent with a partial rupture of the tendon

What they're measuring

the change in thickness of Achilles tendon

Timeframe: at first week and after 12 week of treatment

the change in Pain in patients with non-insertional Achilles tendinopathy.

Timeframe: at first week and after 12 week of treatment

the change in Functional performance

Timeframe: at first week and after 12 week of treatment