CompletedNot Applicable

The Effects of Intensity on Exercise-Induced Hypoalgesia During a Knee Extension Exercise

United States60 participantsStarted 2022-10-31

Plain-language summary

The primary purpose of this study is to to compare immediate changes in pressure pain threshold at the exercising muscle (quadriceps) and a non-exercising muscle (upper trapezius) during low and high weight knee extension exercise. Participants will attend one session that consists of pain sensitivity testing, completion of pain-related psychological questionnaires, and random assignment to one of three interventions: 1) knee extension exercise with a high weight, 2) knee extension exercise with a low weight, or 3) quiet rest.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pain-free * 18-60 years old * Participant can appropriately perform the knee extension exercise (assessed during screening) Exclusion Criteria: * Non-English speaking * Regular use of prescription pain medications * Current or history of chronic pain condition * Currently taking blood-thinning medication * Systemic medical condition known to affect sensation, such as uncontrolled diabetes or neurological conditions * Any contraindication to the application of ice, such as: uncontrolled hypertension, cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, circulatory compromise * Known presence of cardiovascular, pulmonary, or metabolic disease * Current use of tobacco products * Not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+) * Surgery, injury, or fracture to the lower back or lower extremity within the past 6 months

What they're measuring

Pressure Pain Threshold

Timeframe: 1 day

Trial details

NCT IDNCT05561582

SponsorUniversity of Central Florida

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-03-27

Results submitted2024-05-31