Effects of Peppermint Oil in Mild-moderate Hypertension. (NCT05561543) | Clinical Trial Compass
CompletedNot Applicable
Effects of Peppermint Oil in Mild-moderate Hypertension.
United Kingdom40 participantsStarted 2024-01-01
Plain-language summary
Cardiovascular and associated hypertensive diseases are the leading health burden and cause of mortality worldwide; therefore, the necessity for effective interventions is paramount. Dietary interventions to improve cardiovascular health are highly sought after as they possess less risk and financial burden than pharmacological drugs. Our previous randomized trial has shown that oral peppermint can improving systolic blood pressure and other cardiovascular/ blood lipids in healthy individuals. However, to date, no research has explored this using a placebo randomized intervention in patients with hypertension.
Therefore, the primary purpose of the proposed investigation is to test the ability of oral peppermint oil supplementation to improve cardiometabolic parameters in participants with mild-moderate hypertension.
Who can participate
Age range18 Years – 65 Years
SexALL
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Inclusion criteria
✓. Aged from 18-65 years
✓. Systolic blood pressure 120 to 139 mmHg
✓. Not taking prescribed medicine for blood pressure management
✓. have the ability to complete written questionnaires independently
✓. Able to provide informed consent
Exclusion criteria
✕. diagnosed diabetes mellitus
✕. known cardiovascular disease or clinically significant cardiovascular comorbidity, including coronary heart disease, symptomatic heart failure, clinically significant arrhythmia, or a history of stroke or transient ischaemic attack within the previous 6 months
✕. known or suspected secondary hypertension, including renal, renovascular, or endocrine causes
✕. known clinically significant renal impairment or severe hepatic disease