UnknownNot Applicable

Competition Induced Hyperglycemia in Athletes With Type 1 Diabetes

Denmark24 participantsStarted 2023-05-01

Plain-language summary

Design and methods 12 athletes with T1D and 12 healthy athletes are included in a prospective experimental randomized, cross-over study. Athletes are provided with a Dexcom G6 CGM to measure glucose excursions before, during and after exercise and a Holter ECG-E-patch to measure HRV. Psychological stress levels are assessed from Competitive State Anxiety Inventory-2. The athletes are studied on two occasions: Day 1: 5K running competition and Day 2: 5K high intensity training session (running) in the athletes' regular training environment. Endpoints Primary endpoints: Change in plasma glucose from start of exercise to end of exercise during competition compared to training. Secondary endpoints: Hormonal response (cortisol, adrenalin, noradrenaline). Changes in heart rate and HRV before, during and after exercise. CGM-glucose and plasma glucose discrepancies.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * T1D and healthy athletes who are otherwise healthy * Age between 18 and 65 years * HbA1c less than 70 mmol/mol * The athletes must be engaged in competitive sports that includes running, and agree to participate in a local 5 km running competition within 3 months Exclusion Criteria: * Proliferative retinopathy * Hypoglycemia unawareness * Heart disease and other conditions which may be negatively affected by the VO2 max test and study days

What they're measuring

Plasma glucose

Timeframe: Plasma glucose is measured Twenty minutes before the start of the competition until 60 minutes after the competition.

Trial details

NCT IDNCT05561517

SponsorUniversity of Aarhus

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-01-21