HEaling LIght Algorithms for the ICU Patient

Inclusion Criteria: * Patient capable of giving consent or additionally existing legal caregiver/authorized representative in case of non-consenting patients in the intensive care unit * Male and female patients with age ≥ 18 years * Expected intensive care unit stay ≥ 5 days * Invasive mechanical ventilation or non-invasive mechanical ventilation (with positive ventilation pressure \> 6 hours/day or high flow \>30 liters) on the day of ICU admission Exclusion Criteria: * Participation in other clinical studies during the study period and ten days before * Patients with psychiatric diseases * Patients with a history of stroke and known severe residual cognitive deficits * Patients with a history of cardiopulmonary arrest or pulseless electric activity with cardiopulmonary resuscitation followed by therapeutic hypothermia during entire hospital stay * Analphabetism * Anacusis or Hypoacusis with hearing aid device, Amaurosis * Lacking willingness to save and hand out data within the study * Accommodation in an institution due to an official or judicial order * History of sleep-related breathing disorders * History or suspicion of hypoxic brain damage * History or suspicion of elevated intracranial pressure in the last 7 days before study inclusion * Patients with an open chest after cardiac surgery * Patient has a power of attorney or patient's provision, where he/she refuses participation in any clinical trial * The informed consent of the patient or the subject's legally a…