Postoperative Pulmonary Complications (PPC) are common. It severely affects postoperative recovery, particularly in abdominal surgery. Several studies showed that intraoperative lung-protective ventilation with periodic lung recruitment maneuvers could reduce postoperative pulmonary complications. Other studies showed that intraoperative lung protective ventilation without periodic lung recruitment maneuvers could also reduce postoperative pulmonary complications. The purpose of this study was to compare the effects of the above two regimens on postoperative pulmonary complications.
Who can participate
Age range18 Years
SexALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
✓. Undergoing elective major abdominal surgery (expected duration of mechanical ventilation ≥2 h)
✓. had an intermediate to high risk of developing postoperative pulmonary complications as indicated by an Assess Respiratory Risk in Surgical Patients in Catalonia score (≥26)
✓. Pulse oxygen saturation in room air ≥ 94%
Exclusion criteria
✕. younger than 18 years
✕. had received invasive mechanical ventilation for longer than 1 h within the last 2 weeks prior to surgery
✕. had a history of pneumonia within 1 month prior to surgery
✕. had severe chronic obstructive pulmonary disease or pulmonary bullae
✕. had a progressive neuromuscular illness
✕. severe heart dysfunction (New York Heart Association classification ≥4)
✕. with an American Society of Anesthesiologists (ASA) physical status of IV or higher
What they're measuring
1
Rate of respiratory failure
Timeframe: Day 0 to 7 after surgery
Trial details
NCT IDNCT05556174
SponsorSixth Affiliated Hospital, Sun Yat-sen University