UnknownPhase 4

Endoscopic Hemostatic and Sedative Treatment of Esophageal and Gastric Variceal Bleeding

China60 participantsStarted 2022-02-10

Plain-language summary

Remazolam besylate was used for sedation during endoscopic hemostasis in patients with esophageal and gastric varices rupture and bleeding in liver cirrhosis. The onset time, recovery time and incidence of adverse reactions were observed.

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients diagnosed with bleeding from ruptured esophageal and gastric varices * Endoscopic hemostatic treatment was performed * Body Mass Index(BMI)18～28kg/m2 Exclusion Criteria: * History or evidence of increased risk of sedation/anesthesia; * Pregnant and lactating women; * Have participated in other drug trials within 30 days prior to enrollment; * those with contraindications to propofol, opioids and their remedies; * Unwilling to sign informed consent.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Sedation scores

Timeframe: From the begin to 48 hours after procedure

Trial details

NCT IDNCT05554965

SponsorRenmin Hospital of Wuhan University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-10-30

Contact for this trial

Lu Wang

15927142942 410669243@qq.com

View on ClinicalTrials.gov More Endoscopic Hemostasis trials

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.