UnknownNot Applicable

The Debridement To Treat The Traumatic Corneal Abrasion

China156 participantsStarted 2022-12-31

Plain-language summary

Patients who signed informed consent to participate in the study will receive corneal epithelial deplasia. The patient was instructed to follow up closely in the following year, and the recurrence of the patient was collected through wechat follow-up.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. The affected eye is traumatic corneal epithelial abrasion, and the specific criteria are as follows: A: Damage caused by one of the three high risk causes of recurrent corneal epithelial exfoliation defined as fingernails, paper, or plant leaves; B: Monocular disease; C: Eye pain, tears, photophobia and foreign body sensation when injured; D: Local defect of corneal epithelium was found at the time of injury, and fluorescein sodium staining was positive; E: The time from injury to first diagnosis is less than 24 hours.
✓. Be between the ages of 18 and 60.
✓. Patients volunteered to participate in the study and signed the informed consent, showing good compliance.

Exclusion criteria

✕. Corneal epithelial defect complicated with infection.
✕. Patients with other ocular surface diseases (such as eyelid insufficiency, eyelid gland dysfunction, Sjogren's syndrome, bullae keratopathy, corneal dystrophy, drug induced corneal toxicity, etc.).
✕. Pre-existing corneal disease (corneal degenerative disease or viral keratitis, etc.) or history of corneal surgery;
✕. Long-term contact lens wearers.
✕. Pregnant or lactating women; Severe impairment of heart, liver and kidney function; One who is mentally abnormal; People with other inflammatory or autoimmune diseases. Corneal epithelial defect complicated with infection

What they're measuring

wound recurrence

Timeframe: month 12 after treatment

Trial details

NCT IDNCT05534217

SponsorZhongshan Ophthalmic Center, Sun Yat-sen University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-01

Contact for this trial

Zhaohui Yuan, Doctor's degree

13570961208 yuanzhaohui.@gzzoc.com

View on ClinicalTrials.gov More Corneal Abrasion trials