Compression Therapy as a Prophylactic Method Against CIPN: a Prospective Self-controlled Trial

Inclusion Criteria: * Age range from 18 to 70 * ECOG physical status score: 0-2 * Newly diagnosed patients who have not received antitumor therapy * Nasopharyngeal carcinoma confirmed by pathology * Paclitaxel is included in the chemotherapy regimen * Laboratory examination results within one week before enrollment should meet the following conditions: neutrophils (ANC) ≥1.5×109/L, platelets (PLT) ≥80×109/L, total bilirubin (TBI) ≤1.5× upper limit of normal value (2mg/ dL), ALT and AST ≤2× upper limit of normal value * Patients voluntarily participate and provide written informed consent Exclusion Criteria: * Patients with peripheral neuropathy, hand-foot syndrome, and dermatomyositis * Patients with missing fingers or toes * Patients with Raynaud's syndrome and peripheral vascular ischemia * Pregnant or lactating women * Those considered unsuitable for inclusion by the researcher