RecruitingNot Applicable

Cognition and Imaging With Tigertriever

United States424 participantsStarted 2024-10-28

Plain-language summary

The objective of the COGNITIVE Study is to evaluate whether successful reperfusion with Tigertriever is associated with cognitive benefit.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patients admitted with large vessel occlusion (LVO) and treated with the Tigertriever, as indicated per the approved IFU.
. Tigertriever was used as the first line treatment in the target vessel.
. A signed informed consent.
. Age 18-75 years (inclusive).
. No known significant pre-stroke disability (pre-stroke mRS 0 or 1).

Exclusion criteria

. Use of any other IA recanalization device prior to the Tigertriever in the target vessel, including aspiration catheter.
. Evidence of acute brain hemorrhage on CT and/or MRI at admission.
. Prior hemorrhage, stroke, thrombolysis, and/or endovascular therapy in the last 3 months.
. Probable cerebral amyloid angiopathy.
. Pre-stroke diagnosed dementia and/or prescribed cholinesterase inhibitors.
. Pre-stroke diagnosed and/or currently treated major depression.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Association between successful reperfusion* and cognitive benefit**

Timeframe: 180 days post treatment

Trial details

NCT IDNCT05531461

SponsorRapid Medical

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2026-11

Contact for this trial

Walid Haddad, Dr.

+972 72 2503331 walid@rapid-medical.com

View on ClinicalTrials.gov More Stroke trials