CompletedNot Applicable

Quantification and Characterization of Circulating Epithelial and Endothelial Cells in Gougerot-Sjögren Syndrome, Compared to Systemic Sclerosis

France40 participantsStarted 2022-09-27

Plain-language summary

Primary Gougerot-Sjögren's syndrome is a systemic autoimmune disease belonging to the group of connectivities, whose physiopathology remains largely unknown. Quantification and characterization of epithelial and endothelial circulants in Gougerot-Sjögren's syndrome could reflect the intensity of the epithelial aggression, and thus possibly constitute a biomarker.

Who can participate

Age range18 Years

SexFEMALE

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Inclusion Criteria: * Female patients over the age of 18 * Written and signed consent by the participant and the investigator * Affiliated person or beneficiary of the social security system * Test group: patients with Gougerot-Sjögren's syndrome connectivitis meeting the ACR/EULAR classification criteria * Positive control group: patients with diffuse systemic scleroderma connectivitis meeting ACR/EULAR classification criteria Exclusion Criteria: * Association of the two diseases in the same patient * Progressive cancer * Subject protected by law, under guardianship or curatorship * Inability to give free and informed consent to participate in the study * Withdrawal of consent

What they're measuring

Circulating epithelial cell detection rate

Timeframe: day 0

Trial details

NCT IDNCT05528809

SponsorUniversity Hospital, Montpellier

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-10-12

View on ClinicalTrials.gov More Primary Gougerot-Sjögren Syndrome trials