CompletedNot Applicable

SMILE Trial - Imaging Sub-Study

Canada11 participantsStarted 2023-03-07

Plain-language summary

This is a pilot sub-study of an ongoing trial comparing N2O to midazolam in MDD and will examine neuroimaging correlates of treatment response.

Who can participate

Age range18 Years – 65 Years

SexALL

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Inclusion Criteria: * Eligible for main nitrous oxide (SMILE) study Exclusion Criteria: * Contraindication for undergoing MRI scans (e.g., hip circumference \< 180 cm or metal in the body)

What they're measuring

Brain functional activity and connectivity

Timeframe: 4 weeks from the baseline visit

Trial details

NCT IDNCT05528718

SponsorUnity Health Toronto

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-03-30

View on ClinicalTrials.gov More Major Depressive Disorder trials