The Time-Dependent Development of Incisional Hernias in Emergency Laparotomy Incisions of High-Ri… (NCT05528692) | Clinical Trial Compass
WithdrawnNot Applicable
The Time-Dependent Development of Incisional Hernias in Emergency Laparotomy Incisions of High-Risk Patients
Stopped: Collaboration stopped
Denmark0Started 2025-11
Plain-language summary
The aim of this study is to describe the development of symptomatic and asymptomatic incisional hernias after emergency midline laparotomy over time in high-risk patients evaluated by consecutive MRI-scans.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Unscheduled midline laparotomy in an emergency or subacute setting, involving perforated bowel, bowel obstruction, bowel ischemia (due to mesenteric vascular disease or incarceration), inflammatory diseases (e.g. diverticulitis, appendicitis, ulcerative colitis, cholecystitis and Crohn's disease), abscesses, non-traumatic intraabdominal bleeding or any emergency re-operation to elective surgery
* Age of 18 years or above
* BMI above 27
* At least one risk factor for incisional hernia i.e. earlier midline laparotomy, BMI \> 30, abdominal aortic aneurysm or prior surgery for abdominal aortic aneurysm, active smoking, liver cirrhosis, re-laparotomy, age \> 75, history of primary ventral hernia (treated or untreated before index surgery), large laparotomy involving more than 2/3 of the abdominal wall as measured from the xiphoid process to the pubic bone
Exclusion Criteria:
* Malign, incurable disease
* Other reasons for short life expectancy \<2 year as evaluated by the investigator
* Midline-incisions \<15 cm
* Mesh augmentation of abdominal wall closure at index surgery or earlier mesh augmentation of the abdominal wall
* Severe claustrophobia or any other mental habitus, making it impossible to perform MRI-scan without sedation
* Metallic magnetic implants that serves as a contraindication for MRI-scan (including pacemakers, large tattoos, insulin pumps, etc.)
* Metallic prosthetic non-magnetic implants that are suspected to create severe artefacts on…
What they're measuring
1
Early (30-days) MRI-diagnosed, incisional hernia development in high-risk patients after emergency midline laparotomy.