Echocardiographic Evaluation of RV Injury in the ICU (NCT05525936) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Echocardiographic Evaluation of RV Injury in the ICU
440 participantsStarted 2024-08-01
Plain-language summary
The adequate characterization of RV injury is currently unknown. The hypothesis is that the best characterization of RV injury is the one with the most significant impact on the response to fluids and on the outcome. An RV failure is expected to induce fluid-unresponsiveness and potentially worst outcome.
The main objective is to characterize different types of RV injury in critically ill patients by examining their association, including predictive performances, in hemodynamics parameters, ventilation parameters, and clinical outcomes
The study will be based on the realisation of an echocardiography within 48 hours following inclusion.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients admitted to intensive care unit
* With a central venous catheter inserted in the superior vena cava territory or a pulmonary arterial catheter for their management,
* Requiring invasive ventilation, and/or catecholamine infusion.
Exclusion Criteria:
* Advanced chronic heart failure,
* Planned or unplanned surgery including cardiac,
* Advanced cancer,
* Child C cirrhosis,
* Contraindication to PLR and volume expansion,
* Age \< 18 years,
* Pregnancy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Classification performance of selected haemodynamic parameters, ventilation parameters and biomarkers in different types of right ventricular injuries
Timeframe: Through study completion, an average of 1 year.
2
Association of the three different types of RV injury with ICU mortality
Timeframe: Through study completion, an average of 1 year