Effect of Nasal Positive Airway Pressure Versus Standard Care on Oxygenation and Ventilation During Propofol-based Sedation for Colonoscopy in Patients With High Risk of Airway Obstruction

Inclusion Criteria: * Patients undergoing colonoscopy * American Society of Anesthesiology (ASA) Physical Status I-III * BMI ≥30 kg/m2 or suspected Obstructive Sleep Apnea Exclusion Criteria: * Inpatient status * Active Congestive Heart Failure Exacerbation * Untreated ischemic heart disease * Acute exacerbation of respiratory disorders, including Chronic obstructive pulmonary disease (COPD) and asthma * Emergent procedures * Pregnancy * Previous enrollment in this study * Inability to provide informed consent * Additional medical testing planned for the same day * History of allergic reaction to Propofol * Tracheostomy * Supra-glottic or sub-glottic tumor * Gastrointestinal tract obstruction or delayed transit (including delayed gastric emptying, gastric bezoar, achalasia, toxic megacolon). * Prisoners * Unable to fit SuperNoVa