intraduction and aim In this study, in cases who will undergo elective day colonoscopy under sedoanalgesia; It was planned to investigate the effects of restrictive and liberal fluid administration on hemodynamics, side effects, drug levels, patient satisfaction, recovery and discharge times during the procedure. Methods This study was planned to be conducted as a prospective, randomized (closed envelope method), controlled, double-blind study with 100 adult patients aged 18-65 years in the american sociological association (ASA I-II) risk group who will undergo colonoscopy under sedation-analgesia under elective conditions.Vascular access will be opened and randomly divided into two groups as Group R (Restrictive, 2ml/kg 0.9% Sodium cloride-NaCl during colonoscopy) and Group L (Liberal 15ml/kg 0.9% NaCl during colonoscopy). For sedoanalgesia, Midazolam 0.02 mg/kg, Fentanyl 1 μg/kg, Ketamine 0.3 mg/kg will be administered intravenous (IV), followed by 10 mg additional doses of propofol until the Ramsay sedation score (RSS) is 3-4. All colonoscopy procedures will be performed by the same gastroenterologist. Expectations and scientific contributions This research may help to understand the effects of giving or not administering intravenous fluids (restrictive/liberal) prior to the procedure in patients undergoing elective colonoscopy under sedoanalgesia. It can provide hemodynamic stability, reduction in drug doses, reduction of side effects, rapid recovery and discharge, and reduction of costs.
Age range
18 Years – 65 Years
Sex
ALL
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Comparison of systolic blood pressure in restrictive and liberal patients in colonosopy under sedoanalgesia.
Timeframe: During colonoscopy
Comparison of diastolic blood pressure in restrictive and liberal patients in colonosopy
Timeframe: During colonoscopy
Comparison of heart rate in restrictive and liberal patients in colonosopy
Timeframe: During colonoscopy
Comparison of spO2 in restrictive and liberal patients in colonosopy
Timeframe: During colonoscopy
Comparison of procedure times in restrictive and liberal patients in colonosopy
Timeframe: During colonoscopy
Comparison of total anaesthetic doses in restrictive and liberal patients in colonosopy
Timeframe: During colonoscopy
Comparison of nose and vomiting and other effects in restrictive and liberal patients in colonosopy
Timeframe: 24 hours
Comparison of sedation levels in restrictive and liberal patients in colonosopy
Timeframe: 24 hours