Acute Plasma Abeta Responses to Stress

Inclusion Criteria: * Healthy adult weighing at least 110 pounds * No chronic conditions or illness * Taking no medications or drugs that might alter the stress response (e.g., corticosteroids, beta-blockers, and others) * Not using any hormone-containing medication (e.g., hormonal contraceptives, hormone replacement, etc.) * No contraindications for cold pressor test exposure (high blood pressure, heart disease, dysrhythmia, peripheral vascular disease, any other cardiovascular disorder, diabetes, vasculitis, lupus, tingling or numbness in the hands and/or feet, cryoglobulinemia, and Reynaud's phenomenon) * No history of fainting during blood draws * No phobia of having their blood drawn * No general history of fainting or seizures * Not currently diagnosed with a mood disorder (e.g., major depressive disorder) * Not pregnant in the past 12 months * Not lactating in the past 12 months * Not trying to become pregnant if premenopausal * Experienced natural menopause if postmenopausal * Be non-smokers * Be fluent in English Exclusion Criteria: \- Unwilling to be filmed during the stress task OR unwilling to sign the waiver allowing their filmed responses to be used in scientific presentations