UnknownPhase 2/3

Caffeine Kinetics and CrossFit®-Specific Performance

Poland25 participantsStarted 2022-06-29

Plain-language summary

The study aims at assessing the relation between caffeine (CAF) and paraxanthine (PAX) kinetics after acute ingestion of caffeine (3 mg/kg body mass) in the form or mono- or multi-ingredient preparations and CrossFit®-specific performance or selected indicators of psychophysiological state. Blood indicators of muscle damage/recovery, acid-base balance and electrolytes levels will be evaluated. The impact of genetic variations in the polymorphisms rs5751876 in ADORA2A gene and rs762551 in CYP1A2 on CAF/PAX kinetics will be considered.

Who can participate

Age range

18 Years – 40 Years

Sex

MALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * written informed consent from all participants before the study, * a current medical clearance to practice sports, * training experience any sport discipline ≥ 5 years and training experience in HIFT ≥ 2 years, * performing ≥3 training units per week, * participating in CrossFit® competitions at least once a year. Exclusion Criteria: * current injury, * any health-related contraindication, * declared general feeling of being unwell, * unwilling to follow the study protocol, * serious disease or metabolic problems, * smoking and tobacco use, * presence of infectious disease in the previous 4 weeks of the study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

The effect of acute ingestion of the same dose of caffeine (3 mg/kg BM) in form of 3 different preparations on discipline-specific performance

Timeframe: 60 minutes after ingestion of tested supplements/placebo

Trial details

NCT IDNCT05516212

SponsorPoznan University of Physical Education

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-07-29

Contact for this trial

Krzysztof Durkalec-Michalski, Prof., PhD

+48 (61) 835 51 65 durkalec-michalski@awf.poznan.pl

View on ClinicalTrials.gov More Supplementation trials