UnknownNot Applicable

Speeded Anomia Treatment in Chronic Post-stroke Aphasia

United Kingdom100 participantsStarted 2023-01-15

Plain-language summary

The main aim of the study is to investigate the effect of a novel, speeded anomia therapy (Conroy et al., 2018) in a large population of patients with chronic post-stroke aphasia. The treatment will be delivered via a web application (QuickWord).

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Native English speakers * Age 18 years or above * Stroke (any type) greater than 12 months post onset * No history of neurological disorders / psychiatric disorders * Normal or corrected-to-normal hearing \& vision * Able to give informed consent * Currently not receiving Speech \& Language therapy * Minimal repetition skills (\>40% on an immediate word repetition test) * Evidence of naming difficulties (\<90% in Boston Naming Test - Goodglass et al., 1983) Exclusion Criteria: * Non-native English speakers * Less than 18 years old * Stroke less than 12 months post onset * History of neurological disorders / psychiatric disorders * Uncorrected hearing \& vision * Unable to give informed consent * Currently receiving Speech \& Language therapy * Insufficient repetition skills (\<40% on an immediate word repetition test) * Good naming performance (\>90% in Boston Naming Test - Goodglass et al., 1983)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Speeded anomia therapy effect in reaction time

Timeframe: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)

Speeded anomia therapy effect in accuracy

Timeframe: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)

Generalisation to connected speech

Timeframe: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)

Trial details

NCT IDNCT05512884

SponsorUniversity of Cambridge

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-09-01

Contact for this trial

Eleni Zevgolatakou, MSc

+447724386296 Elena.Zevgolatakou@mrc-cbu.cam.ac.uk

View on ClinicalTrials.gov More Aphasia trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Speeded anomia therapy effect in reaction time

Timeframe: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)

Speeded anomia therapy effect in accuracy

Timeframe: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)

Generalisation to connected speech

Timeframe: Measured over 10 weeks (Week 0, Week 2, Week 4, Week 6, Week 10)