UnknownPhase 1/2

Breast Stimulation vs. Low Dose Oxytocin Augmentation for Labor Induction

Israel200 participantsStarted 2022-10

Plain-language summary

To find the preferred method of labor induction (birth augmentation) for women with a history of one prior cesarean section scar and in grandmultiparas, the difference in time interval from augmentation to delivery will be measured between breast stimulation vs. low-dose oxytocin administration in this prospective single-center randomized controlled trial.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Inclusion criteria

✓. Singleton vertex gestations at or beyond 37 weeks of gestation
✓. History of one prior cesarean section scar or grandmultipara (birth number 6 and above),
✓. Spontaneous onset of labor or after labor induction by Foley balloon catheter, eligible for this trial
✓. Determined by the obstetrics care team that augmentation was needed.
✓. Augmentation will be initiated at or beyond 2.5 cm dilation, with or without ruptured membranes and uterine activity less than 3 contractions in 10 minutes on tocodynamometry.

Exclusion criteria

✕. History of two prior cesarean section scars,
✕. Younger than 18 years,
✕. Any contraindication for vaginal birth (placenta previa, vasa previa, cord presentation, inadequate pelvis, prior uterine rupture),
✕. Fetuses in nonvertex presentation
✕. Fetuses with suspected life-limiting anomalies,
✕. Suspected abruption or bleeding of unknown origin,
✕. Women who did not agree to the enter the study.

What they're measuring

Time interval from augmentation of labor to delivery

Timeframe: up to 48 hours

Trial details

NCT IDNCT05510310

SponsorWestern Galilee Hospital-Nahariya

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2024-10

Contact for this trial

Maya Wolf, MD

050-7887800 MayaW@gmc.gov.il

View on ClinicalTrials.gov More Labor Onset and Length Abnormalities trials