Delayed cord clamping is a routine technique used in the delivery room. The baby remains attached to the umbilical cord and placenta for 30-60 seconds after birth to allow for maximal transfer of oxygen and blood to the newborn. This study seeks to determine the best position (on the back versus on the belly) for the newborn during the 30-60 seconds of delayed cord clamping.
Who can participate
Age range
18 Years – 55 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Pregnant patient admitted for diagnosis that could result in a preterm delivery
* Anticipated gestational age of delivery could be between 25w+0d - 29w+6d
* Fetus without major anomalies or known genetic condition that could impact respiratory status or need for intubation at birth
* Singleton or twin gestation
* Neonate eligible for delayed cord clamping based on institutional protocol
* Patient is able to understand study procedures and is willing and able to consent
Exclusion Criteria:
* Triplet or higher order gestation
* Maternal or fetal/neonatal contraindication to delayed cord clamping
* Major fetal anomaly that would be expected to impact delivery room intubation rates such as:
* Major congenital cardiac defect (not isolated atrial septal defect/ventricular septal defect)
* Significant fetal arrhythmia at the time of delivery
* Fetal tumor
* Renal anhydramnios (not isolated urinary tract dilation with normal fluid)
* Congenital Diaphragmatic Hernia
* Heterotaxy
* Moderate to severe ventriculomegaly or other major brain malformation (not mild isolated ventriculomegaly)
* Airway obstruction
* Underlying genetic disease that could impact respiratory function at delivery
* Arthrogryposis (not apparently isolated clubbed foot)
* Skeletal dysplasia
* Pregnant patient is unable to understand study materials or is unwilling or unable to consent
* Acute maternal obstetric emergency that precludes time or maternal focus for the c…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of pre-term neonates that require endotracheal intubation
Timeframe: 30-60 seconds immediately after birth of the newborn