The purpose of this study is to investigate the effects of intravenous lidocaine on serum miRNA-135a and its downstream proteins Rock2 and Add1 in elderly patients undergoing non-cardiac under general anesthesia.
Age range
65 Years – 80 Years
Sex
ALL
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A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Changes from Baseline miRNA-135A at the end of surgery immediately and 1, 3days after surgery
Timeframe: at preoperation, at the end of surgery immediately, 1day and 3day after surgery
Changes from Baseline Rock2 at the end of surgery immediately and 1, 3days after surgery
Timeframe: at preoperation, at the end of surgery immediately, 1day and 3day after surgery
Changes from Baseline Add1 at the end of surgery immediately and 1, 3days after surgery
Timeframe: at preoperation, at the end of surgery immediately, 1day and 3day after surgery