Design of a Genetic Score to Predict the Response to a Dietary Intervention in Adults With Metabolic Syndrome

Inclusion Criteria: * Adults (men and women) between the ages of 18 and 60. * Adults mexican mestizos (parents and grandparents born in Mexico). * Adults who can read and write. * Adults willing/able to provide informed consent. * Adults with obesity (BMI ≥ 30 and ≤ 39 kg / m2). * Adults with at least one of the metabolic syndrome diagnostic criteria: Waist circumference: men \> 102 cm or women \> 88 cm. Hypertriglyceridemia \>150 mg/dL High fasting glucose \>100 mg/dL High blood pressure ≥ 130/85 mmHg Low HDL-cholesterol: men \<40 mg/dL and women \< 50 mg/dL Exclusion Criteria: * Adults with any type of diabetes. * Adults with hypertension. * Adults with kidney disease diagnosed by a medical or with creatinine\> 1.3 mg / dL for men and \> 1.1 mg / dL for women and / or blood urea nitrogen (BUN)\> 20 mg / dL. * Adults with acquired diseases that produce obesity and diabetes secondarily. * Adults who have suffered a cardiovascular event. * Adults with weight loss \> 3 kg in the last 3 months. * Adults with any catabolic diseases such as cancer and/or AIDS. * Gravidity status * Adults who smoke * Adults in treatment with any medication