CompletedNot Applicable

Immune Response and Affective States of Elderly and 50+ Individuals After Intentional and Indirect Contact With Nature

Brazil54 participantsStarted 2023-06-20

Plain-language summary

Randomized clinical trial on the influence of intentional and indirect contact with nature on the immune response and affective states in people aged 50 years or older.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * individuals of both sexes * capable of physical and mental to carry out the proposed activities * capable of mental to fill in the questionnaires. Exclusion Criteria: * autoimmune diseases * chronic or acute inflammatory diseases * disease that affects the response of the immune system * neuromuscular problems * oncological diseases and neoplastic * individuals being treated with immunosuppressive drugs or that affect the immune system * individuals who are under the influence of alcohol or other substances that interfere with cognitive ability * those who have had contact intentional relationship with nature in the 30-day period prior to participating in the study

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change from Baseline Concentration of Cytokines in Soluble Immune Profile at 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention.

Timeframe: immediately pre intervention, 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention

Change from baseline percentage and absolute number levels of Cellular Immune Profile at 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention

Timeframe: immediately pre intervention, 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention.

Change from baseline percentage and absolute number levels of Cellular Immune Profile (others) at 30 minutes post intervention, within 48 hours and within 4 weeks post intervention

Timeframe: immediately pre intervention, 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention.

Trial details

NCT IDNCT05492006

SponsorHospital Israelita Albert Einstein

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-11-30

View on ClinicalTrials.gov More Elderly trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Change from Baseline Concentration of Cytokines in Soluble Immune Profile at 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention.

Timeframe: immediately pre intervention, 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention

Change from baseline percentage and absolute number levels of Cellular Immune Profile at 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention

Timeframe: immediately pre intervention, 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention.

Change from baseline percentage and absolute number levels of Cellular Immune Profile (others) at 30 minutes post intervention, within 48 hours and within 4 weeks post intervention

Timeframe: immediately pre intervention, 30 minutes post intervention, within 48 hours post intervention and within 4 weeks post intervention.