Active — Not RecruitingNot Applicable

The Motility Mother-Child Cohort

Denmark250 participantsStarted 2022-08-22

Plain-language summary

The overall aim of the project is to investigate how bowel habits and nutrition in early life relate to the infant gut microbiome and metabolome from birth to 1 year of age. By unravelling links between these factors in early life, we might be able to identify new putative mechanisms by which diet via microbiota-dependent pathways affects intestinal motility in early life. Furtermore, it will be explored how the development of the gut microbiome associates with the child´s development.

Who can participate

Age range18 Years – 40 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Mothers Inclusion Criteria: * Age: 18-40 years of age at inclusion * Speaking Danish (since all written and oral information will be in Danish) * Willing to store their child's biological samples in a small closed container in their own freezer at home Mothers Exclusion Criteria: * Gestational age more than 34 weeks at time of recruitment * Diagnosed with gestational diabetes during this current pregnancy * Diagnosed with preeclampsia during this current pregnancy * Diagnosed with any severe or chronic diseases\* * Expecting triplets or higher order of multiple pregnancy * Concurrent participation in another study * Not capable of following the examinations according to the investigator´s instructions Infants Inclusion Criteria: \- Gestational age at birth: 36 weeks or later Infants Exclusion Criteria: \- Severe chronic illness

What they're measuring

Infant gut microbiome composition

Timeframe: Faecal samples collected bi-weekly from birth until 12 months

Trial details

NCT IDNCT05491161

SponsorUniversity of Copenhagen

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-01-01

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