Effects of Upper Extremity Manual Lymphatic Drainage on Symptom Severity, Hand Functions, Electro… (NCT05490420) | Clinical Trial Compass
CompletedNot Applicable
Effects of Upper Extremity Manual Lymphatic Drainage on Symptom Severity, Hand Functions, Electrophysiological and Ultrasonographic Measurements in Carpal Tunnel Syndrome
Turkey (Türkiye)27 participantsStarted 2022-09-05
Plain-language summary
This study is aimed to investigate the effects of upper extremity manual lymphatic drainage, which is applied to remove edema from the carpal tunnel region in addition to conventional exercise therapy in Carpal tunnel syndrome patients on findings of clinical, ultrasonographic, and electrophysiological.
Who can participate
Age range
40 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* People aged between 40-60 years
* Having been diagnosed with carpal tunnel syndrome (CTS) at least 6 months ago or having symptoms related to carpal tunnel syndrome for at least 6 months
* Having mild (median nerve sensory conduction velocity below 40 m/sec) and moderate (median nerve sensory conduction velocity below 40 m/sec and median motor distal latency 4 ms and above) CTS according to electrophysiological findings
* Not having received medical treatment and/or physiotherapy for CTS in the last 6 months
Exclusion Criteria:
* Having cervical radiculopathy
* Having thoracic outlet syndrome
* Presence of systemic disease that may lead to CTS, such as diabetes or thyroid disease
* Pregnancy
* Presence of anemia
* Having a history of CTS surgery
* Presence of radial or ulnar nerve sensory-motor lesions accompanying the present condition
* Presence of lymphedema
* Having severe (Sensory nerve action potential cannot be obtained) and severe (Sensory nerve action potential cannot be obtained, but combined muscle action potential is not present) CTS according to electrophysiological findings
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Symptom severity
Timeframe: Change from baseline symptom severity at week 6 and 10.
2
Grip strength
Timeframe: Change from baseline grip strength at week 6 and 10.
3
Pressure pain threshold (PPT)
Timeframe: Change from baseline pressure pain threshold at week 6 and 10.
4
Cross-sectional area of the median nerve
Timeframe: Change from baseline cross-sectional area of the median nerve at week 6 and 10.
5
Sensory Velocity of median nerve
Timeframe: Change from baseline Sensory Velocity of median nerve at week 6 and 10.
6
Motor velocity of median nerve
Timeframe: Change from baseline motor velocity of median nerve at week 6 and 10.