CompletedNot Applicable

Correlation Study of PAI-1 4G/5G Polymorphism and Postoperative AKI in Patients With Aortic Dissection

China283 participantsStarted 2022-04-28

Plain-language summary

To explore the association between PAI-1 4G5G polymorphism and the risk of CSA-AKI in Stanford type A dissection patients undergoing open-heart repair surgery.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Stanford type A aortic dissection patient admitted to the Department of Cardiology, in Xijing Hospital * Open thoracic aortic dissection correction (total aortic arch replacement with or without aortic valve replacement) is proposed * Age ≥ 18 years old * Informed consent has been signed Exclusion Criteria: * Cardiopulmonary bypass assisted cardiac surgery has been performed in the past three months * Renal failure patients who have started or are receiving dialysis treatment before operation

What they're measuring

Number of participants who develop postoperative moderate to severe AKI

Timeframe: from time of the end of surgery; assessed up to 7 days

Trial details

NCT IDNCT05490394

SponsorXijing Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-06-16

View on ClinicalTrials.gov More AKI - Acute Kidney Injury trials