CompletedPhase 4

Alveolar Ridge Preservation With Putty Allograft vs. Putty Alloplast Graft

United States30 participantsStarted 2022-10-06

Plain-language summary

The primary aims of this study are to compare, after 4 months, the clinical and histologic results of a combination demineralized/mineralized putty allograft vs. synthetic calcium phosphosilicate (CPS) putty alloplast graft utilization in socket preservation procedures. A regenerative tissue matrix membrane will be used to cover each graft lying below the flap.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Have one non-molar tooth requiring extraction that will be replaced by a dental implant.
✓. Healthy male or female who is at least 18 years old.
✓. Patients must sign an informed consent approved by the University of Louisville Human Studies Committee.

Exclusion criteria

✕. Patients with debilitating systemic diseases, or diseases that have a clinically significant effect on the periodontium.
✕. Presence or history of osteonecrosis of jaws.
✕. Patients who are currently taking IV bisphosphonates or who had IV treatment with bisphosphonates irrespective of duration.
✕. Patients who have been treated with oral bisphosphonates for more than three years.
✕. Patients with an allergy to any material or medication used in the study.
✕. Patients who need prophylactic antibiotics
✕. Previous head and neck radiation therapy.
✕. Chemotherapy in the previous 12 months.

What they're measuring

Alveolar ridge width

Timeframe: 4 months

Alveolar ridge height

Timeframe: 4 months

Buccal soft tissue thickness

Timeframe: 4 months

Trial details

NCT IDNCT05484492

SponsorUniversity of Louisville

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-07

View on ClinicalTrials.gov More Alveolar Bone Resorption trials