RecruitingNot Applicable

Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor

Israel600 participantsStarted 2022-11-25

Plain-language summary

This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine related obstetrical outcome and infectious morbidity

Who can participate

Age range18 Years – 48 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: maternal age \> 18 years singleton pregnancy vertex presentation prolonged \>18 h prom or preterm delivery \- Exclusion Criteria: * GBS carrier * preterm premature rupture of membrane for conservative treatment * intra-uterine fetal death fetal major anomaly * drug allergy for the antibiotic in use in this study * women receiving antibiotic treatment for other infection such as urinary tract infection

What they're measuring

endometritis rate

Timeframe: up to 6 weeks postpartum

chorioamnionitis rate

Timeframe: during labor (up to delivery of the newborn)

Trial details

NCT IDNCT05469984

SponsorWestern Galilee Hospital-Nahariya

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2025-09-25

Contact for this trial

Maya Wolf, MD

972-50-7887800 mayaw@gmc.gov.il

View on ClinicalTrials.gov More Preterm Labor With Preterm Delivery trials