Active — Not RecruitingNot Applicable

Bicruciate-retaining (2C) Total Knee Arthroplasty (TKA) Versus Posterior-stabilized (PS) Total Knee Arthroplasty (TKA)

Canada77 participantsStarted 2011-01-01

Plain-language summary

Total knee arthroplasty (TKA) with the sacrifice of the anterior cruciate ligament is the standard treatment for severe knee osteoarthritis. A number of studies on the kinematics of the prosthetic knee tend to show that implants that preserve the cruciate ligaments best reproduce the kinematics of the healthy knee. The goal is to compare the clinical and radiological results in patients undergoing total knee replacement surgery according to the type of prosthesis used. It is anticipated that the bicruciate-retaining prosthesis will result in better function of the operated knee than the posterior-stabilized prosthesis. Method: * Randomized controlled trial * Monocentric * Randomization will be done using sealed envelopes

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients awaiting a total knee replacement who are candidates for a bi-cruciate retaining prosthesis * Disabling bicompartmental gonarthrosis with failure of conservative treatment * 70 years of age or younger at the time of the pre-operative consultation * Intact and functional cruciate ligaments * Coronal knee malalignment of 10 degrees or less * Adequate preoperative range of motion, defined as maximum flexum (inability to fully extend the knee) of 10 degrees and flexion greater than 90 degrees * Adequate intraoperative knee exposure to allow preservation of both cruciate ligaments Exclusion Criteria: * Inability to undergo an EOS examination, defined as the inability to stand or morbid obesity (inability of the patient to enter the EOS machine, which is relatively cramped) * Inability to walk on a treadmill and squat * Pregnant women to avoid unnecessary fetal radiation * Illiteracy, language barrier and any other reason that prevents patients from answering the questionnaires

What they're measuring

Change in KOOS pain score

Timeframe: Change from baseline (pre surgery) KOOS pain score at 10 years after the surgery

Trial details

NCT IDNCT05469776

SponsorCentre hospitalier de l'Université de Montréal (CHUM)

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2031-12-31