CompletedNot Applicable

Diagnostic Biomarkers to Correlate Molecular Changes and Inflammatory Cascade in the Dental Pulp.

Egypt48 participantsStarted 2020-12-12

Plain-language summary

This study aimed to evaluate the molecular changes that occur within the pulp tissue during inflammation and its correlation with vital pulp therapy with its different treatment modalities (Direct pulp capping, Partial Pulpotomy and Complete Pulpotomy).

Who can participate

Age range15 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Positive response to cold testing. * The age range from 15-45 years. * Patients of both sex. * Has clinical symptoms of pulpitis with normal apical tissues and supported by radiographic evaluation with no periradicular changes. Exclusion Criteria: * Patients over 45 years of age. * Patients with clinical symptoms of periradicular inflammation or periradicular radiographic changes. * Negative response to cold testing.

What they're measuring

Periradicular condition of the teeth

Timeframe: 6 months

Level of Interleukin 8 in pulpal blood

Timeframe: 6 months

Trial details

NCT IDNCT05464797

SponsorMansoura University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-06-01

View on ClinicalTrials.gov More Vital Pulp Therapy trials