Cross-linked Volume-stable Collagen Matrix Versus Connective Tissue Graft At Implant Site.

Inclusion Criteria: * Age ≥18 years. * No systemic diseases or pregnancy. * Self-reported smoking ≤10 cigarettes/day. * No probing depths ≥5 mm * Full-mouth plaque score (FMPS) and full-mouth bleeding score (FMBS) ≤15% (measured at four sites per tooth). * Single dental implant with a scheduled for soft tissue augmentation procedure at the time of uncovering. * Need of soft tissue augmentation for aesthetic purpose and/or functional reasons * No previous soft tissue augmentation procedure at experimental site. Exclusion Criteria: * General contraindications for dental and/or surgical treatments * Concurrent or previous immunosuppressant, bisphosphonate or high dose corticosteroid therapy * Inflammatory and autoimmune disease of oral cavity * History of myeloma, respiratory tract cancer, breast cancer, prostate cancer or kidney cancer requiring chemotherapy or radiotherapy within the past five years * Radiotherapy of head area * Disease or condition affecting connective tissue metabolism (e.g. disease of arteries in the operating zone, bone metabolic diseases, alcohol abuse, treatment with anticoagulants) * Any systemic diseases that affect bone metabolism (e.g thyroid dysfunction, autoimmune disease) * Untreated acute periodontal disease * Patients who smoke more than 10 cigarettes/day will be excluded from the study * Diabetes * Allergy to the collagen * Pregnant or lactating women * Women of child bearing age, not using a highly effective method of birth control * Partic…