Doravirine and Weight Gain in Antiretroviral Naive

Inclusion Criteria: * 18 years or older; * No prior exposure to antiretroviral therapy for \>7 days prior to study entry; * Plasma HIV1 RNA concentration \>/=5000 copies/mL; * CD4 T cell count \>/=200 cells/µL. * For persons capable of becoming pregnant, negative serum or urine pregnancy test within 45 days prior to entry * Ability and willingness of participant or legal guardian/representative to provide informed consent Exclusion Criteria: * Evidence of resistance to DOR, TDF, 3TC/FTC or BIC. * Creatinine clearance \<60 mL/min * Use of weight loss agents or plans to initiate weight loss program (diet or exercise-based) * Known allergy/sensitivity or any hypersensitivity to components of study drug(s) or their formulation