CompletedNot Applicable

The Flapless Approach in Periodontal Regeneration

Italy46 participantsStarted 2022-09-01

Plain-language summary

The present investigation is designed in order to compare the radiographic and clinical effectiveness of flapless procedure performed alone or in combination with enamel matrix derivatives in the periodontal regenerative treatment of deep intrabony defects in patients with moderate or severe periodontitis. The study will have a follow-up of 12 months.

Who can participate

Age range18 Years – 70 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * diagnosis of periodontitis stage III or IV; * presence of at least one tooth with ≥6 mm associated with a radiographic intrabony defect ≥3 mm at least 2 months after the completion of non-surgical therapy; * a full-mouth plaque score and full-mouth bleeding score \<15% at the time of the experimental procedure; * signed informed consent. Exclusion Criteria: * relevant medical disorders contraindicating periodontal surgery or detrimental to periodontal healing; * consumption of drugs known to affect periodontal status; * pregnancy and lactation; * third molars, teeth with furcation involvement or inadequate endodontic treatment and/or prosthetic restoration; * heavy smokers \>10 cigarettes per day.

What they're measuring

Clinical attachment level change

Timeframe: 12 months

Trial details

NCT IDNCT05456555

SponsorUniversity of Turin, Italy

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-01

View on ClinicalTrials.gov More Periodontitis, Adult trials