CompletedNot Applicable

Brain Health With Inner Engineering Meditation

United States77 participantsStarted 2023-01-06

Plain-language summary

This study will explore whether a 21-minute meditation practice called Shambhavi Mahamudra Kriya leads to changes in brain health and explore how it affects cognitive and physiological function.

Who can participate

Age range

20 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Individuals between the ages of 20-65 years. * Subjects will be required to be able to understand study instructions and provide informed consent. * Currently residing in Massachusetts. Exclusion Criteria: * Non-English Speaking. (Justification: Meditation and cognitive assessment instruments are not validated in a sufficient range of languages, and the research team lacks polylingual capabilities or the financial resources to hire interpreters for the duration of all proposed assessments.) * Practicing meditation regularly for the past 6 months (3 or more times per week of practice regularly for the past 6 month). * History of psychiatric illness such as severe anxiety, severe depression, Schizophrenia or bipolar disorder. * History of any form of cognitive decline or neurological conditions such as dementia, Parkinson's disease, Alzheimer's disease, Huntington's disease, brain tumors, brain surgery. * Current use of cognition enhancing drugs * Current management for chronic pain. * History (within the last 5 years) of stroke/aneurysm. * Active history (within the last 5 years) of alcohol or drug abuse (\> 10 drinks per week). * Current pregnancy or planning to become pregnant in the next 6 months. * Currently enrolled in another interventional study that could impact the primary outcome, as determined by the PI. * Educational attainment below high school level or equivalent. * Significant visual impairment. Women of childbearing potential will be i…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Frontal Midline Theta Power after 6 Months of Daily Meditation Practice

Timeframe: Measured at Baseline and 6 months

Change in Gamma Slope Index (GSI) after 6 Months of Daily Meditation

Timeframe: Measured at Baseline and 6 months

Trial details

NCT IDNCT05455814

SponsorBeth Israel Deaconess Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-16

View on ClinicalTrials.gov More Meditation trials

Who can participate

Age range

20 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.